- You currently are currently being treated for erectile dysfunction (eg. using Viagra, Cialis)
- Hemoglobin A1c >= 10% and/or diabetic end organ damage (eg. neuropathy, retinopathy)
- Major Depressive Disorder
- Bipolar Disorder
- Psychosis or Schizophrenia
- History of Non-arteritic Anterior Ischemic Optic Neuropathy
- History of Heart Attack
- History of Stroke (CVA) and/or TIA
- History of Valvular Replacement or Disease
- History of Peripheral Vascular Disease
- History of glaucoma (specifically narrow-angle type)
- History of seizures or epilepsy
- End-stage kidney and/or liver disease
- Sickle Cell
- Liver disease or dysfunction
- Currently taking other SSRIs or MAO inhibitors
- History of bleeding disorders
- Allergy to Paroxetine, Sertraline, or Lidocaine-prilocaine